samon - Sensitivity Analysis for Missing Data
In a clinical trial with repeated measures designs,
outcomes are often taken from subjects at fixed time-points.
The focus of the trial may be to compare the mean outcome in
two or more groups at some pre-specified time after enrollment.
In the presence of missing data auxiliary assumptions are
necessary to perform such comparisons. One commonly employed
assumption is the missing at random assumption (MAR). The
'samon' package allows the user to perform a (parameterized)
sensitivity analysis of this assumption. In particular it can
be used to examine the sensitivity of tests in the difference
in outcomes to violations of the MAR assumption. The
sensitivity analysis can be performed under two scenarios, a)
where the data exhibit a monotone missing data pattern (see the
samon() function), and, b) where in addition to a monotone
missing data pattern the data exhibit intermittent missing
values (see the samonIM() function).